I was playing my Virtual Boy and it had me thinking that Clickteam Fusion could potentially produce those kinds of games if there was a decent way to do the side by side 3D that would be required to run it on something like a phone inside a google cardboard thing or on a meta quest or similar HMD.
One thought I had is to use sub applications to represent each eye, but I'm not sure how I would make events occur simultaneously in each of them without running into weird issues. and I can't think of how to do it all in one frame because I need to produce the binocular vision effect.
A game similar to Mario Clash would be fairly straight forward as the stage does not need to move, but for anything like a sidescroller I'm currently stumped. Though I still suspect it's possible.
If anyone has any ideas, feel free to share them.