I think this will depend on Your assets organization. I'll be working on that to make it as simple as it can be or maybe You're thinking about online assets packages.Will it be easy to find textures that can fit the 3d scenes that we will create ?
Clickteam Firefly Level Editor I'm making goes 2.5+! Here's some of the latest LVL Edit's feature - spritesheet animations:
Some work in progress level designed in LVL Edit: